Exposure is considered the most active element of cognitive behavioral therapy (CBT) for pediatric anxiety. Yet many youth do not respond to CBT, and exposure is the component patients most often find difficult to tolerate. Cognitive control and its supporting neural substrates may enhance exposure efficacy by helping youth remain engaged with feared stimuli despite urges to avoid. However, little work has identified how exposure-based CBT modulates intrinsic connectivity of tripartite networks that support cognitive control (e.g., central executive [CEN], salience [SN], and default mode networks [DMN]), limiting efforts to develop strategies to improve and personalize treatment. — Excerpt from Journal of the American Academy of Child & Adolescent Psychiatry Read More
Exposure-Focused Cognitive Behavioral Therapy Increases Connectivity Between the Central Executive and Salience Networks in Pediatric Anxiety
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